ISSN 2149-5807 | E-ISSN 2149-6048
Original Article
Evaluation of Patients with Ischemic Stroke Receiving iv t-PA in the Emergency Department
1 Department of Emergency Medicine, Trakya University School of Medicine, Edirne, Turkey  
2 Department of Emergency Medicine, Nevsehir State Hospital, Nevsehir, Turkey  
3 Department of Emergency Medicine, Sultan 1. Murat State Hospital, Edirne, Turkey  
4 Department of Emergency Medicine, Unye State Hospital, Ordu, Turkey  
5 Department of Radiology, Erciyes University School of Medicine, Kayseri, Turkey  
6 Department of Neurology, Erciyes University School of Medicine, Kayseri, Turkey  
7 Department of Emergency Medicine, Erciyes University School of Medicine, Kayseri, Turkey  
Eurasian J Emerg Med 2018; 17: 50-54
DOI: 10.5152/eajem.2018.30922
Key Words: Emergency medicine, ischemic stroke, tissue plasminogen activator


Aim: The aim of the present study was to determine the demographic characteristics, localization of emboli, imaging findings, National Institutes of Health Stroke Scale (NIHSS) scores, and complications of patients who received intravenous (iv) tissue plasminogen activator (t-PA) due to early period of ischemic cerebrovascular disease (CVD) during the 6-year period in a tertiary level emergency department of a university hospital.

Materials and Methods: The study was retrospectively performed in 65 patients aged ≥18 years and who underwent iv t-PA with a diagnosis of ischemic CVD. Demographic data, such as age, gender, and smoking, were obtained by examining the medical records of the patients. The baseline Glasgow Coma Scale, NIHSS, start time of the event, time of admission to the hospital, and prognosis of the patients were recorded.

Results: Intracranial hemorrhage was detected in 16.9% of the patients after treatment. On examination of the patients’ outcome, a total of 32.3% (n=21) died after therapy. A significant correlation was observed between high NIHSS score and complications.

Conclusion: In our study, a high NIHSS score at the time of admission has been found to increase both the risk of intracerebral hemorrhagic complication and mortality. We hypothesize that iv t-PA treatment gives successful results despite the complications, and emergency physicians should be more courageous in their application.

Cite this article as: Salt O, Baykan N, Kaymaz ND, Yakar S, Donmez S, Donmez H, et al. Evaluation of Patients with Ischemic Stroke Receiving iv t-PA in the Emergency Department. Eurasian J Emerg Med. 2018; 17: 50-4.

Key Words
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AVES | Copyright © 2018 Emergency Medicine Physicians Association of Turkey | Latest Update: 15.10.2018