ISSN 2149-5807 | E-ISSN 2149-6048
1 Department of Emergency Medicine, Ankara Atatürk Training And Research Hospital, Ankara, Turkey  
2 Department of Emergency Medicine, Yıldırım Beyazıt University, Ankara, Turkey  
Eurasian J Emerg Med ; : -


Aim: The aim of our study was to investigate the importance of oxidative stress levels in the diagnosis and prognosis of acute pancreatitis.


Materials and Methods: 55 patients with acute pancreatitis and 47 healthy volunteers were included in the study. The study group was divided into three subgroups according to CT severity index. Group 1 consisted of patients with CT severity index score 0-2, Group 2 consisted of patients with CT severity index 3-6, where Group 3 consisted of patients with CT severity index 7-10. Total oxidant stress (TOS), total antioxidant stress (TAS) and oxidative stress index (OSI) were compared between study and control groups.


Results: Mean age of the study group was significantly higher than that of control group (p<0.001). No significant difference was found between groups in terms of sex (p=0.999). TOS (p<0.001), TAS (p<0.011) and OSI (p<0.001) levels were significantly higher in the patient group compared to control group. No significant difference was found between subgroups of the study group (group 1-good prognosis, group 2-moderate prognosis, group 3-poor prognosis) with respect to TOS (p=0.844), TAS (p=0.600) and OSI (p=0.846) levels.



Conclusion: Whereas our study does not support the use of oxidative stress parameters for prediction of severity and prognosis in patients with acute pancreatitis, additional and larger studies are warranted.

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