ISSN 2149-5807 | E-ISSN 2149-6048
Original Article
Change in Complete Blood Count Parameters and Vital Signs After Intravenous Infusion of 1 Liter of Normal Saline
1 Department of Emergency Medicine, Kecioren Training and Research Hospital, Ankara, Turkey  
2 Department of Emergency Medicine, Ankara Ataturk Training and Research Hospital, Ankara, Turkey  
3 Department of Emergency Medicine, Kocaeli University School of Medicine, Kocaeli, Turkey  
Eurasian J Emerg Med 2018; 17: 71-74
DOI: DOI: 10.5152/eajem.2018.83007
Key Words: Complete blood count, saline solution, vital signs


Aim: In patients with suspected acute hemorrhage in the emergency department, the first-line of treatment is intravenous fluid therapy. The most frequently used parameters to estimate the amount of hemorrhage and to plan the management are the vital signs, hemoglobin (Hb), and hematocrit (Hct) values. In this study, we aimed to define possible changes in the vital signs, Hb, and Hct values after intravenous infusion of 1 L normal saline in non-hemorrhagic patients to interpret the Hb and Hct values in hemorrhagic patients who receive the same treatment.


Materials and Methods: One hundred patients who presented to the emergency department of a training and research hospital between December 1 and 31, 2012, were included in the study. One liter of normal saline was given to patients who consented to participate in the study. The complete blood count parameters and vital signs were recorded before and after administration of saline.

Results: Statistically significant decreases in pulse, systolic blood pressure, white blood cell count, Hb, and Hct values were observed after the administration of saline (p<0.001). The median Hb and Hct values decreased from 14.2 to 13 g/dL (p<0.001) and from 42.4% to 38.3% (p<0.001), respectively.


Conclusion: In the follow-up of patients who are given intravenous fluids, emergency department physicians should consider that some changes may occur in vital signs and complete blood count parameters due to hemodilution.

Cite this article as: Gokcen E, Cevik Y, Pamukcu Gunaydin G, Dogan NO, Tekin M. Changes in Complete Blood Count Parameters and Vital Signs After Intravenous Infusion of 1 Liter of Normal Saline. Eurasian J Emerg Med. 2018; 17: 71-4.

Key Words
Editor’s Corner
AVES | Copyright © 2018 Emergency Medicine Physicians Association of Turkey | Latest Update: 15.10.2018